The HYDRA is built using a combination of IOMMU/VTd capable processor & system board. I selected the Asrock X58 Extreme, with 3x PCIE 16, 2x PCIE 4, & 2 PCI slots. Supports 24GB RAM and is fully populated. There are 4 ATI Radeon 6450's, 1 ATI Radeon 4650, and 1 Nvidia Geforce FX5200 (PCI). There is a 3 port PCI USB card (1 internal, 2 external)