In 1948 Arne Tiselius received the Nobel Prize in Chemistry for "for his research on electrophoresis and adsorption analysis, especially for his discoveries concerning the complex nature of the serum proteins".

Electrophoresis is a method for the separation of macromolecules (DNA, RNA and proteins) and their fragments, based on there size and charge. * Wikipedia

Practically, electrophoresis is the process of running a current, typically at a high voltage, sometimes exceeding several thousands of volts, typically through a gel.

In should come as no surprise that electrophoresis is a very big deal. Without it we would not have sequenced the human genome, or any other genome for that matter. It may, in fact, be the primary enabling technology for all of molecular biology.

There are only a few metals that are suitable for electrodes. Platinum, Palladium, Silver, Mercury, Carbon, and Gold.

Ordinarily, one uses a platinum wire for the electrodes. To use any other material than those listed, say copper, serves only to illustrate profound ignorance.

Platinum is typically used where high currents and durability are needed, Carbon is bio compatible but noisy, Silver is electrically quiet and generally preferred. Mercury makes for very nice electrodes but for obvious reasons and the hysteria associated with it's use only used where very high performance justifies it's downside. Gold works, but other than it's chemical inertness has nothing to recommend it's use.

For signals as might be associated with the measurement of EKG, EEG etc. Silver is the material of choice, actually it's a bit more severe than that. It's the only usable material.

So, what does this mean in practical terms. The electrodes will always be attached via a wire. If you take a look at EEG systems all over the world, thousands of them. People sitting in chairs, with a cap on there head studded with electrodes with wires running off to a box generally out of the frame. Same way for EKG systems, millions of them, electrodes stuck on the chest with wires leading off to a box.

For someone who is to benefit from the use of a prosthetic device the hard reality is that the device get soiled and dirty. It will need to be cleaned. People need to put on their prosthetic device like they put on their socks! When the device get dirty, they need to throw it into the wash with their jeans, T-shirts, and dirty rags from washing the car.

The reality is that is is a long, long, ... long way from sitting in a chair playing a video game using your EEG to sitting in a wheel chair as an ALS patient and navigating across a busy intersection on your way to work. In one case, perhaps you''ll make the evening news showing off, once again, just like it's been done many times before of using the EEG for some kind of "thought controlled" gizmo, to actually helping people go about their lives in a routine fashion that is no more news worthy than today's weather.

It is the paradigm of electrodes connected to boxes with wires that MUST be broken. Totally destroyed! Relegated to the dustbin of history.

Electrodes must be connected to their supporting electronics directly. Electrodes, electronics, connectors, and housing reduced to something the size of a coin "token". And so when you hear your change rattling around in the dryer you'll know that you can either wear it or spend it.

That's why I've gone to the trouble of making PCBs using a ceramic technology. It's the only practical, technologically proven way to connect silver bio electrodes to the electronics in one integral body.