All RF systems have to take interference into account. I'm not sure how much of an impact it will have on our design, but since I'll be laying out a PCB shortly, I want to get some sort of handle on the potential issues before wasting design effort and weeks of manufacturing time. So far, I've run across a couple very useful documents from TI, and will be researching further...

PCB Design Guidelines for Reduced EMI
RF Shielding: The Art and Science of Eliminating Interference
Michael Ossman's RF Design Recommendations