Back when I was deverloping the PSU burner, I wanted to have the Analog Discovery isolated from the common ground, to avoid noise and other issues. Since I did not have a way to do this, I ended up using a laptop on battery for measurements. But for long term, I needed to have this isolation. Unfortunately, things that can isolate USB at 480Mbps or faster are too expensive to justify.
The ADUM3160 isolator can provide a magnetically isolated 12 Mbps connection, which proved to be good enough. I grabbed one ready made isolator module from ebay for about $12, cheap enough. Well, it is not perfect: the B0505S DC/DC converter provided can only supply 1W and the Analog Discovery is a hungry beast.
Full info here http://www.electrobob.com/analog-discovery-usb-isolation/