Suitable options for "The brain"

MSP430

- Low Power,

- 16 bit

- I used it before, awesome documentation for running of battery

Atmega

- Fairly common(Did I hear Arduino?)

- Possibility to reuse code from Mutable Instruments, Atmegatron, MeeBilp, or Bastl Instuments

ARM

- propbly the most powerful

- Some awesome reference like P6 synthesizer

- A synthesizer running linux, IN MY POCKET?!

PIC32

- Seems to be the way to go for various Synth and MIDI related projects

- MIPS asm is tought at many universities